
Regenerative Cell Therapy
For Rotator Cuff Tears

Eligibility Requirements

Females and males
ages 30 – 75

Experiencing shoulder
pain, or lack of shoulder strength

MRI diagnosis of a
partial rotator cuff tear
(Patients who do not have
an MRI may still apply)
About the Trial
- The clinical study uses regenerative cells in patients who have partial thickness rotator cuff tears. These are tears in the tendon that contribute to shoulder pain, dysfunction, and occupational disability.
- In this study, regenerative cells from your fat tissue will be isolated, concentrated, and injected into your tendon tear. You will receive either a steroid injection or an in injection of your own regenerated cells. *
- More information can be found at www.clinicaltrials.gov.
* The use of regenerative cells is investigational. We are studying the safety and effectiveness of this treatment compared to steroid injections.


About Rotator Cuff Tears
- Rotator cuff tears are the leading cause of shoulder
pain in the US. - These tears are very common, affecting 4 million
Americans every year. As many as half of Americans over the age of 60 have a partial rotator cuff tear. - Treating these tears can be difficult. Unfortunately, many partial tears go on to become full tendon tears that require surgery.
Post Treatment Expectations
Following the procedure day, you’ll have 4 follow-up visits with the physician who performed the procedure:
These visits will include a physical exam, questions about your health history and medications, surveys, lab testing and radiographic exams.


1st Follow up visit:
- Physical Exam
- Shoulder Evaluation

2nd Follow up visit:
- Physical Exam
- Shoulder Evaluation

3rd Follow up visit:
- Physical Exam
- Shoulder Evaluation

4th Follow up visit:
- Physical Exam
- Shoulder Evaluation
- MRI of the shoulder

Who is conducting this
clinical trial?
- InGeneron is a biotechnology company creating
innovative, cell-based technologies for the next
generation of medicine. - For the past 20 years, we have focused on helping
patients impacted by orthopedic conditions. - We are dedicated to developing therapies supported
by quality clinical evidence and approved by the FDA.
About Rotator Cuff Tears
Arizona
Dr. Louise Taber - Arizona Research Center
15601 N. 28th Avenue, Suite 100
Phoenix, AZ 85053
Email: rgledhill@azresearchcenter.com
Tel: +1 (602) 863 6363
Florida
Dr. Manish Gupta - Sports and Orthopedic Center
6280 W. Sample Road Suite 202
Coral Springs, FL 33067
Email: wabdelaziz@advancedresearchfl.com
Tel: 954-302-3047
Dr. Joshua Hackel - Andrews Research & Education Foundation
1020 Gulf Breeze Parkway
Gulf Breeze, FL 32561
Email: chandler.bridges@andrewsref.org
Tel: +1 (850) 916 8584
Dr. Luis Martinez - Universal Axon Clinical Research, LLC
3650 NW 82nd Ave
Doral, FL 33166 Angel Benitez
Email: yhernandez@uaclinical.com
Georgia
Dr. Anthony Grasso - Georgia Institute for Clinical Research
335 Roselane St NW Floor 2, Room 203
Marietta, GA 30060
Email: lee.robinson@lowbackpain.com
Tel: +1 (770) 421 2037
Louisiana
Dr. Jaime Garza - Tulane University School Of Medicine
1440 Canal Street Suite 1700 Unit 8471
New Orleans, LA 70112
Email: mmaurin1@tulane.edu
Tel: +1 (504) 988 9101
North Dakota
Dr. Mark Lundeen - Sanford Health System – Sanford Orthopedics and Sports Medicine
2301 25th Street South
Fargo, ND 58103
Email: stemcelltherapy@sanfordhealth.org
Tel: +1 (605) 312 6020
South Dakota
Dr. Harvey Oliver - Sanford Health System – Sanford Orthopedics and Sports Medicine
1210 W 18th Street Suite G01 Route 6771
Sioux Falls, SD 57104
Email: stemcelltherapy@sanfordhealth.org
Tel: +1 (605) 312 6020
Texas
Dr. Daneshvari Solanki - HD Research
4801 Bissonett St
Bellaire, TX
Email: sveramustafa@minkowitzmd.com
Tel: +1 (713) 367 8548
Dr. Jaime Garza - Texas Plastic Surgery
21 Spurs Lane, Suite #120
San Antonio, Texas 78240
Email: mdramirez@ergclinical.com
Tel: +1 (210)-355-5046

Contact your nearest clinical site to learn more.
Frequently Asked Questions
Stem cells serve as the starting material of the body and the precursor to all other cell types. Stem cells are unspecialized cells capable of transforming into a range of other cell types but also able to replicate themselves to produce more stem cells. The body uses stem cells to heal and regenerate tissues by activating the stem cells to mature into the type of cell needed by the body.
- Regenerative cells are cell types that naturally promote tissue regeneration and homeostasis by facilitating the generation of new cells to replace old or injured cells in a particular tissue. Adipose-derived regenerative cells, also known as Stromal Vascular Fraction, are cells isolated from adipose (fat) tissue, where they are found in high concentrations. Regenerative cells include stem cells, notably vaPS cells, and MSCs, which can mature into multiple cell types, progenitor cells, macrophages, and other cell types that promote tissue regeneration and healing. These cells work together through a complex system of signaling, resulting in synergistic healing effects that are greater than the effect that any one cell type can have on its own.
- Multiple studies show that ADRCs can be effective in treating a variety of soft tissue and bone conditions and have a high safety profile.
If you are interested in joining this study please use the contact button at the top of the page to send us a message or reach out to your nearest clinical site using the map above.